Direct asymmetric syntheses of chiral aldehydes and ketones via N-acyl chiral auxiliary derivatives including chiral Weinreb amide equivalents.
This article covers N-acyl chiral auxiliary-based approaches to the asymmetric synthesis of enantiopure aldehydes and ketones. The use of diastereoisomerically pure N-acyl derivatives of chiral auxiliaries (including chiral Weinreb amide equivalents) and their conversion to the corresponding enantio...
| Main Authors: | , , |
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| Format: | Journal article |
| Language: | English |
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2013
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| _version_ | 1797098775086366720 |
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| author | Davies, S Fletcher, A Thomson, J |
| author_facet | Davies, S Fletcher, A Thomson, J |
| author_sort | Davies, S |
| collection | OXFORD |
| description | This article covers N-acyl chiral auxiliary-based approaches to the asymmetric synthesis of enantiopure aldehydes and ketones. The use of diastereoisomerically pure N-acyl derivatives of chiral auxiliaries (including chiral Weinreb amide equivalents) and their conversion to the corresponding enantiopure aldehydes and ketones in a single synthetic operation by treatment with a hydride reducing agent or an organometallic reagent, respectively, are highlighted. |
| first_indexed | 2024-03-07T05:14:28Z |
| format | Journal article |
| id | oxford-uuid:dcb2ac61-5a87-4769-acaf-d6ecbaf796b0 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T05:14:28Z |
| publishDate | 2013 |
| record_format | dspace |
| spelling | oxford-uuid:dcb2ac61-5a87-4769-acaf-d6ecbaf796b02022-03-27T09:19:25ZDirect asymmetric syntheses of chiral aldehydes and ketones via N-acyl chiral auxiliary derivatives including chiral Weinreb amide equivalents.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:dcb2ac61-5a87-4769-acaf-d6ecbaf796b0EnglishSymplectic Elements at Oxford2013Davies, SFletcher, AThomson, JThis article covers N-acyl chiral auxiliary-based approaches to the asymmetric synthesis of enantiopure aldehydes and ketones. The use of diastereoisomerically pure N-acyl derivatives of chiral auxiliaries (including chiral Weinreb amide equivalents) and their conversion to the corresponding enantiopure aldehydes and ketones in a single synthetic operation by treatment with a hydride reducing agent or an organometallic reagent, respectively, are highlighted. |
| spellingShingle | Davies, S Fletcher, A Thomson, J Direct asymmetric syntheses of chiral aldehydes and ketones via N-acyl chiral auxiliary derivatives including chiral Weinreb amide equivalents. |
| title | Direct asymmetric syntheses of chiral aldehydes and ketones via N-acyl chiral auxiliary derivatives including chiral Weinreb amide equivalents. |
| title_full | Direct asymmetric syntheses of chiral aldehydes and ketones via N-acyl chiral auxiliary derivatives including chiral Weinreb amide equivalents. |
| title_fullStr | Direct asymmetric syntheses of chiral aldehydes and ketones via N-acyl chiral auxiliary derivatives including chiral Weinreb amide equivalents. |
| title_full_unstemmed | Direct asymmetric syntheses of chiral aldehydes and ketones via N-acyl chiral auxiliary derivatives including chiral Weinreb amide equivalents. |
| title_short | Direct asymmetric syntheses of chiral aldehydes and ketones via N-acyl chiral auxiliary derivatives including chiral Weinreb amide equivalents. |
| title_sort | direct asymmetric syntheses of chiral aldehydes and ketones via n acyl chiral auxiliary derivatives including chiral weinreb amide equivalents |
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