Rapsyn mediates subsynaptic anchoring of PKA type I and stabilisation of acetylcholine receptor in vivo.

The stabilisation of acetylcholine receptors (AChRs) at the neuromuscular junction depends on muscle activity and the cooperative action of myosin Va and protein kinase A (PKA) type I. To execute its function, PKA has to be present in a subsynaptic microdomain where it is enriched by anchoring prote...

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Autors principals: Choi, K, Berrera, M, Reischl, M, Strack, S, Albrizio, M, Röder, I, Wagner, A, Petersen, Y, Hafner, M, Zaccolo, M, Rudolf, R
Format: Journal article
Idioma:English
Publicat: 2012