Filgotinib, a JAK1 inhibitor, modulates disease-related biomarkers in rheumatoid arthritis: results from two randomized, controlled phase 2b trials

<p><strong>Introduction:</strong> The Janus kinase (JAK) inhibitor therapeutic class has shown significant clinical benefit in the treatment of rheumatoid arthritis (RA). We sought to gain insight into the mode of action and immunological effects of filgotinib, a JAK1 selective inh...

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Bibliographic Details
Main Authors: Tarrant, J, Galien, R, Li, W, Goyal, L, Pan, Y, Hawtin, R, Zhang, W, Van Der Aa, A, Taylor, P
Format: Journal article
Language:English
Published: Springer Verlag 2020