TNF-α and Th2 cytokines induce atopic dermatitis–like features on epidermal differentiation proteins and stratum corneum lipids in human skin equivalents

TNF-α and Th2 cytokines induce atopic dermatitis–like features on epidermal differentiation proteins and stratum corneum lipids in human skin equivalents

Atopic dermatitis (AD) is a chronic inflammatory skin disease in which the skin barrier function is disrupted. In this inflammatory AD environment, cytokines are upregulated, but the cytokine effect on the AD skin barrier is not fully understood. We aimed to investigate the influence of Th2 (IL-4, I...

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Bibliographic Details
Main Authors: Danso, MO, Van Drongelen, V, Mulder, A, Van Esch, J, Scott, H, Van Smeden, J, El Ghalbzouri, A, Bouwstra, JA
Format: Journal article
Language:English
Published: Elsevier 2014

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