Influenza virus-specific cytotoxic T cells in man; induction and properties of the cytotoxic cell.
Human peripheral blood lymphocytes have been sensitized in vitro to influenza virus antigen. After an induction period of 4--14 days, cytotoxic cells which lyse autologous influenza virus-infected lymphoid cells could be demonstrated. The cytotoxic cell is a T lymphocyte which shows specificity for...
| Príomhchruthaitheoirí: | , |
|---|---|
| Formáid: | Journal article |
| Teanga: | English |
| Foilsithe / Cruthaithe: |
1978
|
| _version_ | 1826300297992994816 |
|---|---|
| author | Mcmichael, A Askonas, B |
| author_facet | Mcmichael, A Askonas, B |
| author_sort | Mcmichael, A |
| collection | OXFORD |
| description | Human peripheral blood lymphocytes have been sensitized in vitro to influenza virus antigen. After an induction period of 4--14 days, cytotoxic cells which lyse autologous influenza virus-infected lymphoid cells could be demonstrated. The cytotoxic cell is a T lymphocyte which shows specificity for sensitizing influenza virus type A or B. It cannot distinguish between major subtypes of influenza A virus. The use of virus-infected normal lymphoid cells as target cells overcame the difficulties of nonspecific killing encountered with some transformed cells. |
| first_indexed | 2024-03-07T05:15:01Z |
| format | Journal article |
| id | oxford-uuid:dcde7a79-e03c-4940-93ec-b69b7b8a5672 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T05:15:01Z |
| publishDate | 1978 |
| record_format | dspace |
| spelling | oxford-uuid:dcde7a79-e03c-4940-93ec-b69b7b8a56722022-03-27T09:20:48ZInfluenza virus-specific cytotoxic T cells in man; induction and properties of the cytotoxic cell.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:dcde7a79-e03c-4940-93ec-b69b7b8a5672EnglishSymplectic Elements at Oxford1978Mcmichael, AAskonas, BHuman peripheral blood lymphocytes have been sensitized in vitro to influenza virus antigen. After an induction period of 4--14 days, cytotoxic cells which lyse autologous influenza virus-infected lymphoid cells could be demonstrated. The cytotoxic cell is a T lymphocyte which shows specificity for sensitizing influenza virus type A or B. It cannot distinguish between major subtypes of influenza A virus. The use of virus-infected normal lymphoid cells as target cells overcame the difficulties of nonspecific killing encountered with some transformed cells. |
| spellingShingle | Mcmichael, A Askonas, B Influenza virus-specific cytotoxic T cells in man; induction and properties of the cytotoxic cell. |
| title | Influenza virus-specific cytotoxic T cells in man; induction and properties of the cytotoxic cell. |
| title_full | Influenza virus-specific cytotoxic T cells in man; induction and properties of the cytotoxic cell. |
| title_fullStr | Influenza virus-specific cytotoxic T cells in man; induction and properties of the cytotoxic cell. |
| title_full_unstemmed | Influenza virus-specific cytotoxic T cells in man; induction and properties of the cytotoxic cell. |
| title_short | Influenza virus-specific cytotoxic T cells in man; induction and properties of the cytotoxic cell. |
| title_sort | influenza virus specific cytotoxic t cells in man induction and properties of the cytotoxic cell |
| work_keys_str_mv | AT mcmichaela influenzavirusspecificcytotoxictcellsinmaninductionandpropertiesofthecytotoxiccell AT askonasb influenzavirusspecificcytotoxictcellsinmaninductionandpropertiesofthecytotoxiccell |