Abnormal prefrontal activation directly related to pre-synaptic striatal dopamine dysfunction in people at clinical high risk for psychosis.

Abnormal prefrontal activation directly related to pre-synaptic striatal dopamine dysfunction in people at clinical high risk for psychosis.

Schizophrenia is characterized by altered prefrontal activity and elevated striatal dopaminergic function. To investigate the relationship between these abnormalities in the prodromal phase of the illness, we combined functional Magnetic Resonance Imaging and (18)F-Dopa Positron Emission Tomography....

Full description

Bibliographic Details
Main Authors:	Fusar-Poli, P, Howes, O, Allen, P, Broome, M, Valli, I, Asselin, M, Montgomery, A, Grasby, P, McGuire, P
Format:	Journal article
Language:	English
Published:	2011

Similar Items

Abnormal frontostriatal interactions in people with prodromal signs of psychosis: a multimodal imaging study.
by: Fusar-Poli, P, et al.
Published: (2010)

Multimodal functional imaging investigation before and after the onset of psychosis.
by: Fusar-Poli, P, et al.
Published: (2009)

Elevated striatal dopamine function linked to prodromal signs of schizophrenia.
by: Howes, O, et al.
Published: (2009)

Transition to psychosis associated with prefrontal and subcortical dysfunction in ultra high-risk individuals.
by: Allen, P, et al.
Published: (2012)

Functional brain networks before the onset of psychosis: A prospective fMRI study with graph theoretical analysis
by: Lord, L, et al.
Published: (2012)

Prefrontal function at presentation directly related to clinical outcome in people at ultrahigh risk of psychosis.
by: Fusar-Poli, P, et al.
Published: (2011)

Effects of acute antipsychotic treatment on brain activation in first episode psychosis: an fMRI study.
by: Fusar-Poli, P, et al.
Published: (2007)

Superior temporal lobe dysfunction and frontotemporal dysconnectivity in subjects at risk of psychosis and in first-episode psychosis.
by: Crossley, N, et al.
Published: (2009)

Philosophical issues in the prodromal phase of psychosis.
by: Broome, M, et al.
Published: (2012)

Altered brain function directly related to structural abnormalities in people at ultra high risk of psychosis: longitudinal VBM-fMRI study.
by: Fusar-Poli, P, et al.
Published: (2011)

Misattributing speech and jumping to conclusions: A longitudinal study in people at high risk of psychosis
by: Winton-Brown, T, et al.
Published: (2015)

The relationship between striatal dopamine and anterior cingulate glutamate in first episode psychosis changes with antipsychotic treatment
by: Jauhar, S, et al.
Published: (2023)

White matter alterations related to P300 abnormalities in individuals at high risk for psychosis: an MRI-EEG study.
by: Fusar-Poli, P, et al.
Published: (2011)

Gray matter alterations related to P300 abnormalities in subjects at high risk for psychosis: longitudinal MRI-EEG study.
by: Fusar-Poli, P, et al.
Published: (2011)

The relationship between striatal dopamine and anterior cingulate glutamate in first episode psychosis changes with antipsychotic treatment
by: Sameer Jauhar, et al.
Published: (2023-05-01)

Impaired verbal self-monitoring in individuals at high risk of psychosis.
by: Johns, L, et al.
Published: (2010)

Vulnerability to psychosis : from neurosciences to psychopathology /
by: Fusar-Poli, Paolo, et al.
Published: (2012)

Endocannabinoid-dopamine interactions in striatal synaptic plasticity
by: Brian Neil Mathur, et al.
Published: (2012-04-01)

Delusional ideation, manic symptomatology and working memory in a cohort at clinical high-risk for psychosis: a longitudinal study.
by: Broome, MR, et al.
Published: (2012)

Thalamic glutamate levels as a predictor of cortical response during executive functioning in subjects at high risk for psychosis.
by: Fusar-Poli, P, et al.
Published: (2011)

Spatial working memory in individuals at high risk for psychosis: longitudinal fMRI study.
by: Fusar-Poli, P, et al.
Published: (2010)

Reduced mismatch negativity predates the onset of psychosis.
by: Shaikh, M, et al.
Published: (2012)

Abnormal P300 in people with high risk of developing psychosis.
by: Bramon, E, et al.
Published: (2008)

Neurofunctional correlates of vulnerability to psychosis: a systematic review and meta-analysis.
by: Fusar-Poli, P, et al.
Published: (2007)

Are we really mapping psychosis risk? Neuroanatomical signature of affective disorders in subjects at ultra high risk
by: Modinos, G, et al.
Published: (2014)

Are we really mapping psychosis risk? Neuroanatomical signature of affective disorders in subjects at ultra high risk
by: Modinos, G, et al.
Published: (2014)

Convergent evidence for abnormal striatal synaptic plasticity in dystonia
by: David A. Peterson, et al.
Published: (2010-03-01)

A kinetic model of dopamine- and calcium-dependent striatal synaptic plasticity.
by: Takashi Nakano, et al.
Published: (2010-02-01)

Signaling models for dopamine-dependent temporal contiguity in striatal synaptic plasticity.
by: Hidetoshi Urakubo, et al.
Published: (2020-07-01)

Alterations in white matter evident before the onset of psychosis.
by: Carletti, F, et al.
Published: (2012)

Physical Health and Transition to Psychosis in People at Clinical High Risk
by: De Micheli, A, et al.
Published: (2024)

Cognitive dysfunction and prefrontal synaptic abnormalities in a mouse model of fragile X syndrome
by: Krueger, Dilja, et al.
Published: (2011)

Slow habituation of arousal associated with psychosis proneness.
by: Allen, P, et al.
Published: (2007)

Synaptic Zn2+ potentiates the effects of cocaine on striatal dopamine neurotransmission and behavior
by: Juan L. Gomez, et al.
Published: (2021-11-01)

Mapping the implementation and challenges of clinical services for psychosis prevention in England
by: Andrés Estradé, et al.
Published: (2023-01-01)

Real World Implementation of a Transdiagnostic Risk Calculator for the Automatic Detection of Individuals at Risk of Psychosis in Clinical Routine: Study Protocol
by: Paolo Fusar-Poli, et al.
Published: (2019-03-01)

Cortical control of striatal dopamine transmission via striatal cholinergic interneurons
by: Kosillo, P, et al.
Published: (2016)

Delusion formation and reasoning biases in those at clinical high risk for psychosis.
by: Broome, MR, et al.
Published: (2007)

Lack of evidence to favor specific preventive interventions in psychosis: a network meta‐analysis
by: Davies, C, et al.
Published: (2018)

Parsing neurobiological heterogeneity of the clinical high-risk state for psychosis: A pseudo-continuous arterial spin labelling study
by: Dominic Oliver, et al.
Published: (2023-03-01)