11beta-hydroxysteroid dehydrogenase type 1 activity in lean and obese males with type 2 diabetes mellitus.
Glucocorticoids play an important role in the pathogenesis of obesity and insulin resistance. Impaired conversion of cortisone (E) to cortisol (F) by the type 1 isoenzyme of 11beta-hydroxysteroid dehydrogenase (11beta-HSD) in obesity may represent a protective mechanism preventing ongoing weight gai...
المؤلفون الرئيسيون: | Valsamakis, G, Anwar, A, Tomlinson, J, Shackleton, C, McTernan, P, Chetty, R, Wood, P, Banerjee, A, Holder, G, Barnett, A, Stewart, P, Kumar, S |
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التنسيق: | Journal article |
اللغة: | English |
منشور في: |
2004
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مواد مشابهة
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Cortisol, 11 beta-hydroxysteroid dehydrogenase type 1 and central obesity.
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Low-dose growth hormone inhibits 11 beta-hydroxysteroid dehydrogenase type 1 but has no effect upon fat mass in patients with simple obesity.
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Weight loss increases 11beta-hydroxysteroid dehydrogenase type 1 expression in human adipose tissue.
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Cortisol metabolism and the role of 11beta-hydroxysteroid dehydrogenase.
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