11beta-hydroxysteroid dehydrogenase type 1 activity in lean and obese males with type 2 diabetes mellitus.

11beta-hydroxysteroid dehydrogenase type 1 activity in lean and obese males with type 2 diabetes mellitus.

Glucocorticoids play an important role in the pathogenesis of obesity and insulin resistance. Impaired conversion of cortisone (E) to cortisol (F) by the type 1 isoenzyme of 11beta-hydroxysteroid dehydrogenase (11beta-HSD) in obesity may represent a protective mechanism preventing ongoing weight gai...

Podrobná bibliografie
Hlavní autoři:	Valsamakis, G, Anwar, A, Tomlinson, J, Shackleton, C, McTernan, P, Chetty, R, Wood, P, Banerjee, A, Holder, G, Barnett, A, Stewart, P, Kumar, S
Médium:	Journal article
Jazyk:	English
Vydáno:	2004

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