11beta-hydroxysteroid dehydrogenase type 1 activity in lean and obese males with type 2 diabetes mellitus.

11beta-hydroxysteroid dehydrogenase type 1 activity in lean and obese males with type 2 diabetes mellitus.

Glucocorticoids play an important role in the pathogenesis of obesity and insulin resistance. Impaired conversion of cortisone (E) to cortisol (F) by the type 1 isoenzyme of 11beta-hydroxysteroid dehydrogenase (11beta-HSD) in obesity may represent a protective mechanism preventing ongoing weight gai...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς:	Valsamakis, G, Anwar, A, Tomlinson, J, Shackleton, C, McTernan, P, Chetty, R, Wood, P, Banerjee, A, Holder, G, Barnett, A, Stewart, P, Kumar, S
Μορφή:	Journal article
Γλώσσα:	English
Έκδοση:	2004

Παρόμοια τεκμήρια

Cortisol, 11 beta-hydroxysteroid dehydrogenase type 1 and central obesity.
ανά: Stewart, P, κ.ά.
Έκδοση: (2002)

Low-dose growth hormone inhibits 11 beta-hydroxysteroid dehydrogenase type 1 but has no effect upon fat mass in patients with simple obesity.
ανά: Tomlinson, J, κ.ά.
Έκδοση: (2003)

Weight loss increases 11beta-hydroxysteroid dehydrogenase type 1 expression in human adipose tissue.
ανά: Tomlinson, J, κ.ά.
Έκδοση: (2004)

Cerebrospinal fluid production - A role for 11 beta-hydroxysteroid dehydrogenase type 1?
ανά: Rauz, S, κ.ά.
Έκδοση: (2004)

Cortisol metabolism and the role of 11beta-hydroxysteroid dehydrogenase.
ανά: Tomlinson, J, κ.ά.
Έκδοση: (2001)

11beta-Hydroxysteroid dehydrogenase type 1 regulates insulin and glucagon secretion in pancreatic islets.
ανά: Swali, A, κ.ά.
Έκδοση: (2008)

Reduced 11beta-hydroxysteroid dehydrogenase type 1 activity in obese boys.
ανά: Wiegand, S, κ.ά.
Έκδοση: (2007)

11 beta-hydroxysteroid dehydrogenase type 1 in obese children
ανά: Wiegand, S, κ.ά.
Έκδοση: (2007)

The functional consequences of 11beta-hydroxysteroid dehydrogenase expression in adipose tissue.
ανά: Tomlinson, J, κ.ά.
Έκδοση: (2002)

Expression of 11beta-hydroxysteroid dehydrogenase type 1 in adipose tissue is not increased in human obesity.
ανά: Tomlinson, J, κ.ά.
Έκδοση: (2002)

The role of 11 beta-hydroxysteroid dehydrogenase in central obesity and osteoporosis.
ανά: Tomlinson, J, κ.ά.
Έκδοση: (2000)

11beta-hydroxysteroid dehydrogenase type 1 inhibitors for the treatment of type 2 diabetes.
ανά: Morgan, SA, κ.ά.
Έκδοση: (2010)

Selective inhibitors of 11beta-hydroxysteroid dehydrogenase type 1 for patients with metabolic syndrome: is the target liver, fat, or both?
ανά: Stewart, P, κ.ά.
Έκδοση: (2009)

Mechanisms of disease: Selective inhibition of 11beta-hydroxysteroid dehydrogenase type 1 as a novel treatment for the metabolic syndrome.
ανά: Tomlinson, J, κ.ά.
Έκδοση: (2005)

11beta-hydroxysteroid dehydrogenase type 1: a tissue-specific regulator of glucocorticoid response.
ανά: Tomlinson, J, κ.ά.
Έκδοση: (2004)

Hexose-6-phosphate dehydrogenase confers oxo-reductase activity upon 11 beta-hydroxysteroid dehydrogenase type 1.
ανά: Bujalska, I, κ.ά.
Έκδοση: (2005)

A novel selective 11beta-hydroxysteroid dehydrogenase type 1 inhibitor prevents human adipogenesis.
ανά: Bujalska, I, κ.ά.
Έκδοση: (2008)

Mutations in the genes encoding 11beta-hydroxysteroid dehydrogenase type 1 and hexose-6-phosphate dehydrogenase interact to cause cortisone reductase deficiency.
ανά: Draper, N, κ.ά.
Έκδοση: (2003)

11β-Hydroxysteroid dehydrogenase type 1 as a therapeutic target in the metabolic syndrome
ανά: Tomlinson, J, κ.ά.
Έκδοση: (2005)

Corticosteroids, 11beta-hydroxysteroid dehydrogenase isozymes and the rabbit choroid plexus.
ανά: Sinclair, A, κ.ά.
Έκδοση: (2007)

11beta-hydroxysteroid dehydrogenase type 1 regulates glucocorticoid-induced insulin resistance in skeletal muscle.
ανά: Morgan, SA, κ.ά.
Έκδοση: (2009)

11Beta-hydroxysteroid dehydrogenase type 1 in human disease: a novel therapeutic target.
ανά: Tomlinson, J
Έκδοση: (2005)

11Beta-hydroxysteroid dehydrogenase type 1 in differentiating omental human preadipocytes: from de-activation to generation of cortisol.
ανά: Bujalska, I, κ.ά.
Έκδοση: (2002)

Regulation of expression of 11beta-hydroxysteroid dehydrogenase type 1 in adipose tissue: tissue-specific induction by cytokines.
ανά: Tomlinson, J, κ.ά.
Έκδοση: (2001)

Expression profiling of 11beta-hydroxysteroid dehydrogenase type-1 and glucocorticoid-target genes in subcutaneous and omental human preadipocytes.
ανά: Bujalska, I, κ.ά.
Έκδοση: (2006)

The role of 11beta-hydroxysteroid dehydrogenase 1 in adipogenesis in thyroid-associated ophthalmopathy.
ανά: Tomlinson, J, κ.ά.
Έκδοση: (2010)

Cortisol Metabolism and Hepatic Expression of 11 beta-Hydroxysteroid Dehydrogenase Type 1 in Patients with Non Alcoholic Fatty Liver Disease.
ανά: Ahmed, A, κ.ά.
Έκδοση: (2010)

Role of type-1 11beta-hydroxysteroid dehydrogenase in detoxification processes.
ανά: Maser, E, κ.ά.
Έκδοση: (1997)

Effects of glucocorticoids on fat mass and the therapeutic potential of targeting II beta-hydroxysteroid dehydrogenase type I in obesity
ανά: Tomlinson, J
Έκδοση: (2009)

Androgen generation in adipose tissue in women with simple obesity--a site-specific role for 17beta-hydroxysteroid dehydrogenase type 5.
ανά: Quinkler, M, κ.ά.
Έκδοση: (2004)

Human and rodent type 1 11beta-hydroxysteroid dehydrogenases are 7beta-hydroxycholesterol dehydrogenases involved in oxysterol metabolism.
ανά: Hult, M, κ.ά.
Έκδοση: (2004)

Structure and function of human 17beta-hydroxysteroid dehydrogenases.
ανά: Lukacik, P, κ.ά.
Έκδοση: (2006)

11β-Hydroxysteroid dehydrogenase 1: translational and therapeutic aspects.
ανά: Gathercole, L, κ.ά.
Έκδοση: (2013)

Inhibition of 11beta-hydroxysteroid dehydrogenase type 1 activity in vivo limits glucocorticoid exposure to human adipose tissue and decreases lipolysis.
ανά: Tomlinson, J, κ.ά.
Έκδοση: (2007)

Novel enzymological profiles of human 11beta-hydroxysteroid dehydrogenase type 1.
ανά: Hult, M, κ.ά.
Έκδοση: (2001)

11beta-Hydroxysteroid Dehydrogenase Type 1 Regulation by Intracellular Glucose 6-Phosphate Provides Evidence for a Novel Link between Glucose Metabolism and Hypothalamo-Pituitary-Adrenal Axis Function.
ανά: Walker, E, κ.ά.
Έκδοση: (2007)

Luteal 3beta-hydroxysteroid dehydrogenase and 20alpha-hydroxysteroid dehydrogenase activities in the rat corpus luteum of pseudopregnancy: Effect of the deciduoma reaction
ανά: Telleria Carlos M, κ.ά.
Έκδοση: (2004-05-01)

Cortisol release from adipose tissue by 11beta-hydroxysteroid dehydrogenase type 1 in humans.
ανά: Stimson, R, κ.ά.
Έκδοση: (2009)

A case of 17-beta-hydroxysteroid dehydrogenase deficiency type 3 in adult endocrinologist practice
ανά: N. V. Molashenko, κ.ά.
Έκδοση: (2023-05-01)

Liver X receptors downregulate 11beta-hydroxysteroid dehydrogenase type 1 expression and activity.
ανά: Stulnig, T, κ.ά.
Έκδοση: (2002)