Ultrafine anaphase bridges, broken DNA and illegitimate recombination induced by a replication fork barrier.
Most DNA double-strand breaks (DSBs) in S- and G2-phase cells are repaired accurately by Rad51-dependent sister chromatid recombination. However, a minority give rise to gross chromosome rearrangements (GCRs), which can result in disease/death. What determines whether a DSB is repaired accurately or...
| Päätekijät: | , , , , , , |
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| Aineistotyyppi: | Journal article |
| Kieli: | English |
| Julkaistu: |
Oxford University Press
2011
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Ultrafine anaphase bridges, broken DNA and illegitimate recombination induced by a replication fork barrier
Julkaistu 2011
Journal article