Atypical antipsychotic-induced weight gain

Introduction of a new group of antipsychotic drugs, called atypical because of the proprieties differing them from classical neuroleptics, gave hope for the beginning of a new era in treatment of psychoses, including schizophrenia. Different mechanisms of action not only resulted in a broader spectr...

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Main Authors: Godlewska, B, Olajossy-Hilkesberger, L, Marmurowska-Michałowska, H, Olajossy, M, Landowski, J
Format: Journal article
Language:Polish
Published: 2006
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author Godlewska, B
Olajossy-Hilkesberger, L
Marmurowska-Michałowska, H
Olajossy, M
Landowski, J
author_facet Godlewska, B
Olajossy-Hilkesberger, L
Marmurowska-Michałowska, H
Olajossy, M
Landowski, J
author_sort Godlewska, B
collection OXFORD
description Introduction of a new group of antipsychotic drugs, called atypical because of the proprieties differing them from classical neuroleptics, gave hope for the beginning of a new era in treatment of psychoses, including schizophrenia. Different mechanisms of action not only resulted in a broader spectrum of action and high efficacy but also in a relative lack of extrapiramidal symptoms. However, atypical neuroleptics are not totally free from adverse effects. Symptoms such as sedation, metabolic changes and weight gain, often very quick and severe - present also in the case of classical drugs, but put to the background by extrapiramidal symptoms - have become prominent. Weight gain is important both from the clinical and subjective point of view - as associated with serious somatic consequences and as a source of enormous mental distress. These problems are addressed in this review, with the focus on weight gain associated with the use of specific atypical neuroleptics.
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spelling oxford-uuid:dd239bf4-29fd-4b0d-b5e7-7543481072522022-03-27T09:22:56ZAtypical antipsychotic-induced weight gainJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:dd239bf4-29fd-4b0d-b5e7-754348107252PolishSymplectic Elements at Oxford2006Godlewska, BOlajossy-Hilkesberger, LMarmurowska-Michałowska, HOlajossy, MLandowski, JIntroduction of a new group of antipsychotic drugs, called atypical because of the proprieties differing them from classical neuroleptics, gave hope for the beginning of a new era in treatment of psychoses, including schizophrenia. Different mechanisms of action not only resulted in a broader spectrum of action and high efficacy but also in a relative lack of extrapiramidal symptoms. However, atypical neuroleptics are not totally free from adverse effects. Symptoms such as sedation, metabolic changes and weight gain, often very quick and severe - present also in the case of classical drugs, but put to the background by extrapiramidal symptoms - have become prominent. Weight gain is important both from the clinical and subjective point of view - as associated with serious somatic consequences and as a source of enormous mental distress. These problems are addressed in this review, with the focus on weight gain associated with the use of specific atypical neuroleptics.
spellingShingle Godlewska, B
Olajossy-Hilkesberger, L
Marmurowska-Michałowska, H
Olajossy, M
Landowski, J
Atypical antipsychotic-induced weight gain
title Atypical antipsychotic-induced weight gain
title_full Atypical antipsychotic-induced weight gain
title_fullStr Atypical antipsychotic-induced weight gain
title_full_unstemmed Atypical antipsychotic-induced weight gain
title_short Atypical antipsychotic-induced weight gain
title_sort atypical antipsychotic induced weight gain
work_keys_str_mv AT godlewskab atypicalantipsychoticinducedweightgain
AT olajossyhilkesbergerl atypicalantipsychoticinducedweightgain
AT marmurowskamichałowskah atypicalantipsychoticinducedweightgain
AT olajossym atypicalantipsychoticinducedweightgain
AT landowskij atypicalantipsychoticinducedweightgain