Adherence to a healthy lifestyle and the risk of type 2 diabetes in Chinese adults
Background: Simultaneously adhering to multiple healthy lifestyle factors has been related to up to 90% reduction in type 2 diabetes (T2DM) incidence in White populations; however, little is known about whether such protective effects persist in other non-White populations. Methods: We examined the...
| Principais autores: | , , , , , , , , , , , , |
|---|---|
| Formato: | Journal article |
| Idioma: | English |
| Publicado em: |
Oxford University Press
2017
|
| _version_ | 1826300359334690816 |
|---|---|
| author | Lv, J Yu, C Guo, Y Bian, Z Yang, L Chen, Y Hu, X Hou, W Chen, J Chen, Z Qi, L Li, L and on behalf of the China Kadoorie Biobank Collaborative Group |
| author_facet | Lv, J Yu, C Guo, Y Bian, Z Yang, L Chen, Y Hu, X Hou, W Chen, J Chen, Z Qi, L Li, L and on behalf of the China Kadoorie Biobank Collaborative Group |
| author_sort | Lv, J |
| collection | OXFORD |
| description | Background: Simultaneously adhering to multiple healthy lifestyle factors has been related to up to 90% reduction in type 2 diabetes (T2DM) incidence in White populations; however, little is known about whether such protective effects persist in other non-White populations. Methods: We examined the associations of six lifestyle factors with T2DM in the China Kadoorie Biobank of 461 211 participants aged 30-79 years without diabetes, cardiovascular diseases or cancer at baseline. We defined low-risk lifestyle factors as non-smoking or having stopped for reasons other than illness; alcohol consumption of <30 g/day; upper quarter of the physical activity level; diet rich in vegetables and fruits, low in red meat and with some degree of replacement of rice with wheat; body mass index (BMI) of 18.5-23.9 kg/m 2 ; and waist-to-hip ratio (WHR) <0.90 (men)/<0.85 (women). Results: During a median of 7.2 years of follow-up, we identified 8784 incident T2DM. In multivariable-adjusted analyses, two important risk factors for developing T2DM were higher BMI and WHR. Compared with participants without any low-risk factors, the hazard ratio [95% confidence interval (CI)] for those with at least three low-risk factors was 0.20 (0.19, 0.22). Approximately 72.6% (64.2%, 79.3%) of the incident diabetes were attributable to the combination of BMI, WHR, diet and physical activity. The population attributable risk percentage (PAR%) of diabetes appeared to be similar for men and women, and higher among urban, older and obese participants. Conclusions: Our findings indicate that adherence to a healthy lifestyle may substantially lower the burden of T2DM in the Chinese population. |
| first_indexed | 2024-03-07T05:15:57Z |
| format | Journal article |
| id | oxford-uuid:dd2f4fcf-1299-4a1c-9c3f-a4e77b5ddee1 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T05:15:57Z |
| publishDate | 2017 |
| publisher | Oxford University Press |
| record_format | dspace |
| spelling | oxford-uuid:dd2f4fcf-1299-4a1c-9c3f-a4e77b5ddee12022-03-27T09:23:25ZAdherence to a healthy lifestyle and the risk of type 2 diabetes in Chinese adultsJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:dd2f4fcf-1299-4a1c-9c3f-a4e77b5ddee1EnglishSymplectic Elements at OxfordOxford University Press2017Lv, JYu, CGuo, YBian, ZYang, LChen, YHu, XHou, WChen, JChen, ZQi, LLi, Land on behalf of the China Kadoorie Biobank Collaborative GroupBackground: Simultaneously adhering to multiple healthy lifestyle factors has been related to up to 90% reduction in type 2 diabetes (T2DM) incidence in White populations; however, little is known about whether such protective effects persist in other non-White populations. Methods: We examined the associations of six lifestyle factors with T2DM in the China Kadoorie Biobank of 461 211 participants aged 30-79 years without diabetes, cardiovascular diseases or cancer at baseline. We defined low-risk lifestyle factors as non-smoking or having stopped for reasons other than illness; alcohol consumption of <30 g/day; upper quarter of the physical activity level; diet rich in vegetables and fruits, low in red meat and with some degree of replacement of rice with wheat; body mass index (BMI) of 18.5-23.9 kg/m 2 ; and waist-to-hip ratio (WHR) <0.90 (men)/<0.85 (women). Results: During a median of 7.2 years of follow-up, we identified 8784 incident T2DM. In multivariable-adjusted analyses, two important risk factors for developing T2DM were higher BMI and WHR. Compared with participants without any low-risk factors, the hazard ratio [95% confidence interval (CI)] for those with at least three low-risk factors was 0.20 (0.19, 0.22). Approximately 72.6% (64.2%, 79.3%) of the incident diabetes were attributable to the combination of BMI, WHR, diet and physical activity. The population attributable risk percentage (PAR%) of diabetes appeared to be similar for men and women, and higher among urban, older and obese participants. Conclusions: Our findings indicate that adherence to a healthy lifestyle may substantially lower the burden of T2DM in the Chinese population. |
| spellingShingle | Lv, J Yu, C Guo, Y Bian, Z Yang, L Chen, Y Hu, X Hou, W Chen, J Chen, Z Qi, L Li, L and on behalf of the China Kadoorie Biobank Collaborative Group Adherence to a healthy lifestyle and the risk of type 2 diabetes in Chinese adults |
| title | Adherence to a healthy lifestyle and the risk of type 2 diabetes in Chinese adults |
| title_full | Adherence to a healthy lifestyle and the risk of type 2 diabetes in Chinese adults |
| title_fullStr | Adherence to a healthy lifestyle and the risk of type 2 diabetes in Chinese adults |
| title_full_unstemmed | Adherence to a healthy lifestyle and the risk of type 2 diabetes in Chinese adults |
| title_short | Adherence to a healthy lifestyle and the risk of type 2 diabetes in Chinese adults |
| title_sort | adherence to a healthy lifestyle and the risk of type 2 diabetes in chinese adults |
| work_keys_str_mv | AT lvj adherencetoahealthylifestyleandtheriskoftype2diabetesinchineseadults AT yuc adherencetoahealthylifestyleandtheriskoftype2diabetesinchineseadults AT guoy adherencetoahealthylifestyleandtheriskoftype2diabetesinchineseadults AT bianz adherencetoahealthylifestyleandtheriskoftype2diabetesinchineseadults AT yangl adherencetoahealthylifestyleandtheriskoftype2diabetesinchineseadults AT cheny adherencetoahealthylifestyleandtheriskoftype2diabetesinchineseadults AT hux adherencetoahealthylifestyleandtheriskoftype2diabetesinchineseadults AT houw adherencetoahealthylifestyleandtheriskoftype2diabetesinchineseadults AT chenj adherencetoahealthylifestyleandtheriskoftype2diabetesinchineseadults AT chenz adherencetoahealthylifestyleandtheriskoftype2diabetesinchineseadults AT qil adherencetoahealthylifestyleandtheriskoftype2diabetesinchineseadults AT lil adherencetoahealthylifestyleandtheriskoftype2diabetesinchineseadults AT andonbehalfofthechinakadooriebiobankcollaborativegroup adherencetoahealthylifestyleandtheriskoftype2diabetesinchineseadults |