The notch signalling regulator fringe acts in the Golgi apparatus and requires the glycosyltransferase signature motif DXD.

BACKGROUND: Signalling via the Notch receptor is a key regulator of many developmental processes. The differential responsiveness of Notch-expressing cells to the ligands Delta and Serrate is controlled by Fringe, itself essential for normal patterning in Drosophila and vertebrates. The mechanism of...

Täydet tiedot

Bibliografiset tiedot
Päätekijät: Munro, S, Freeman, M
Aineistotyyppi: Journal article
Kieli:English
Julkaistu: 2000