Origin of diastereocontrol in the oxy-Michael reactions of delta-lactol anions: a computational and experimental study.

The diastereoselectivity in the alkylation and Michael addition of "naked" 6-substituted delta-lactolates has been studied by density functional (B3LYP) calculations with ab initio (MP2) energy refinements. The resulting proposed model for the origins of stereocontrol in this reaction has...

Fuld beskrivelse

Bibliografiske detaljer
Main Authors: Richardson, R, Hernandez-Juan, F, Ward, J, Dixon, D
Format: Journal article
Sprog:English
Udgivet: 2008