Origin of diastereocontrol in the oxy-Michael reactions of delta-lactol anions: a computational and experimental study.
The diastereoselectivity in the alkylation and Michael addition of "naked" 6-substituted delta-lactolates has been studied by density functional (B3LYP) calculations with ab initio (MP2) energy refinements. The resulting proposed model for the origins of stereocontrol in this reaction has...
Main Authors: | Richardson, R, Hernandez-Juan, F, Ward, J, Dixon, D |
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格式: | Journal article |
語言: | English |
出版: |
2008
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