Deprotonation-electrophile trapping of terminal epoxides.

Organolithium-induced deprotonation of terminal epoxides in the presence of appropriate diamine ligands allows trapping with a range of electrophiles, yielding functionalised di- and tri-substituted epoxides in good yields and with control of stereochemistry at the epoxide.

Detalhes bibliográficos
Principais autores: Hodgson, D, Kirton, E, Miles, S, Norsikian, S, Reynolds, N, Coote, S
Formato: Journal article
Idioma:English
Publicado em: 2005