On the genes, genealogies, and geographies of Quebec
Population genetic models only provide coarse representations of real-world ancestry. We used a pedigree compiled from 4 million parish records and genotype data from 2276 French and 20,451 French Canadian individuals to finely model and trace French Canadian ancestry through space and time. The los...
| Main Authors: | , , , , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
American Association for the Advancement of Science
2023
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| _version_ | 1826310133544648704 |
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| author | Anderson-Trocme, L Nelson, D Zabad, S Baya, N Jeffery, B Kelleher, J |
| author_facet | Anderson-Trocme, L Nelson, D Zabad, S Baya, N Jeffery, B Kelleher, J |
| author_sort | Anderson-Trocme, L |
| collection | OXFORD |
| description | Population genetic models only provide coarse representations of real-world ancestry. We used a pedigree compiled from 4 million parish records and genotype data from 2276 French and 20,451 French Canadian individuals to finely model and trace French Canadian ancestry through space and time. The loss of ancestral French population structure and the appearance of spatial and regional structure highlights a wide range of population expansion models. Geographic features shaped migrations, and we find enrichments for migration, genetic, and genealogical relatedness patterns within river networks across regions of Quebec. Finally, we provide a freely accessible simulated whole-genome sequence dataset with spatiotemporal metadata for 1,426,749 individuals reflecting intricate French Canadian population structure. Such realistic population-scale simulations provide opportunities to investigate population genetics at an unprecedented resolution. |
| first_indexed | 2024-03-07T07:46:07Z |
| format | Journal article |
| id | oxford-uuid:dd895bc5-6052-4de2-9c44-5e1dc87f4003 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T07:46:07Z |
| publishDate | 2023 |
| publisher | American Association for the Advancement of Science |
| record_format | dspace |
| spelling | oxford-uuid:dd895bc5-6052-4de2-9c44-5e1dc87f40032023-06-05T13:27:28ZOn the genes, genealogies, and geographies of QuebecJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:dd895bc5-6052-4de2-9c44-5e1dc87f4003EnglishSymplectic ElementsAmerican Association for the Advancement of Science2023Anderson-Trocme, LNelson, DZabad, SBaya, NJeffery, BKelleher, JPopulation genetic models only provide coarse representations of real-world ancestry. We used a pedigree compiled from 4 million parish records and genotype data from 2276 French and 20,451 French Canadian individuals to finely model and trace French Canadian ancestry through space and time. The loss of ancestral French population structure and the appearance of spatial and regional structure highlights a wide range of population expansion models. Geographic features shaped migrations, and we find enrichments for migration, genetic, and genealogical relatedness patterns within river networks across regions of Quebec. Finally, we provide a freely accessible simulated whole-genome sequence dataset with spatiotemporal metadata for 1,426,749 individuals reflecting intricate French Canadian population structure. Such realistic population-scale simulations provide opportunities to investigate population genetics at an unprecedented resolution. |
| spellingShingle | Anderson-Trocme, L Nelson, D Zabad, S Baya, N Jeffery, B Kelleher, J On the genes, genealogies, and geographies of Quebec |
| title | On the genes, genealogies, and geographies of Quebec |
| title_full | On the genes, genealogies, and geographies of Quebec |
| title_fullStr | On the genes, genealogies, and geographies of Quebec |
| title_full_unstemmed | On the genes, genealogies, and geographies of Quebec |
| title_short | On the genes, genealogies, and geographies of Quebec |
| title_sort | on the genes genealogies and geographies of quebec |
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