High-frequency stimulation of the subthalamic nucleus inhibits the firing of juxtacellular labelled 5-HT-containing neurones.

High-frequency stimulation (HFS) of the subthalamic nucleus (STN) is an established neurosurgical therapy for movement disability in advanced Parkinson's disease (PD), but some patients experience psychiatric side-effects like depression. In a previous electrophysiological study, we observed th...

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Hlavní autoři: Hartung, H, Tan, S, Steinbusch, H, Temel, Y, Sharp, T
Médium: Journal article
Jazyk:English
Vydáno: 2011