Functional significance of SRJ domain mutations in CITED2

CITED2 is a transcriptional co-activator with 3 conserved domains shared with other CITED family members and a unique Serine-Glycine Rich Junction (SRJ) that is highly conserved in placental mammals. Loss of Cited2 in mice results in cardiac and aortic arch malformations, adrenal agenesis, neural tu...

Mô tả đầy đủ

Chi tiết về thư mục
Những tác giả chính: Chen, C, Bentham, J, Cosgrove, C, Braganca, J, Cuenda, A, Bamforth, S, Schneider, J, Watkins, H, Keavney, B, Davies, B, Bhattacharya, S
Định dạng: Journal article
Ngôn ngữ:English
Được phát hành: Public Library of Science 2012