Functional significance of SRJ domain mutations in CITED2

CITED2 is a transcriptional co-activator with 3 conserved domains shared with other CITED family members and a unique Serine-Glycine Rich Junction (SRJ) that is highly conserved in placental mammals. Loss of Cited2 in mice results in cardiac and aortic arch malformations, adrenal agenesis, neural tu...

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Main Authors: Chen, C, Bentham, J, Cosgrove, C, Braganca, J, Cuenda, A, Bamforth, S, Schneider, J, Watkins, H, Keavney, B, Davies, B, Bhattacharya, S
格式: Journal article
语言:English
出版: Public Library of Science 2012