Demultiplexing of single-cell RNA-sequencing data using interindividual variation in gene expression

Demultiplexing of single-cell RNA-sequencing data using interindividual variation in gene expression

Motivation: Pooled designs for single-cell RNA sequencing, where many cells from distinct samples are processed jointly, offer increased throughput and reduced batch variation. This study describes expression-aware demultiplexing (EAD), a computational method that employs differential co-expression...

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Detalles Bibliográficos
Main Authors: Nassiri, I, Kwok, AJ, Bhandari, A, Bull, KR, Garner, LC, Klenerman, P, Webber, C, Parkkinen, L, Lee, AW, Wu, Y, Fairfax, B, Knight, JC, Buck, D, Piazza, P
Formato: Journal article
Idioma:English
Publicado: Oxford University Press 2024

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