Has too much cardiology been sent into the appropriateness ORBITA?

The 2017, the Objective Randomised Blinded Investigation With Optimal Medical Therapy of Angioplasty in Stable Angina (ORBITA) trial by Al-Lamee et al1 was the first double-blind, randomised, sham-controlled trial to investigate the role of percutaneous coronary intervention (PCI) for the treatment...

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मुख्य लेखकों: Warriner, DR, O’Sullivan, JW
स्वरूप: Journal article
प्रकाशित: BMJ Publishing Group 2018
विवरण
सारांश:The 2017, the Objective Randomised Blinded Investigation With Optimal Medical Therapy of Angioplasty in Stable Angina (ORBITA) trial by Al-Lamee et al1 was the first double-blind, randomised, sham-controlled trial to investigate the role of percutaneous coronary intervention (PCI) for the treatment of stable angina. It showed no significant difference in exercise tolerance between patients treated with a sham procedure (placebo) and with PCI. Further, patients who underwent PCI had no improvements in other exercise outcomes, nor with any patient-reported endpoints. The results from the ORBITA trial have important implications for clinical practice and research.