D-amino acid oxidase, D-serine and the dopamine system: their interactions and implications for schizophrenia
<p>D-amino acid oxidase (DAO) is a flavin-dependent enzyme that is expressed in the mammalian brain. It is the metabolising enzyme of several D-amino acids, including D serine, which is an endogenous agonist at the glycine co-agonist site of the glutamatergic NMDA receptor. As such, regulation...
Hovedforfatter: | Betts, J |
---|---|
Andre forfattere: | Harrison, P |
Format: | Thesis |
Sprog: | English |
Udgivet: |
2012
|
Fag: |
Lignende værker
-
D-Amino acid oxidase (DAO) activity and expression are increased in schizophrenia
af: Burnet, P, et al.
Udgivet: (2008) -
Investigations of the role of d-amino acid oxidase and serine racemase in schizophrenia
af: Verrall, L
Udgivet: (2008) -
Using neuroimaging and histology to understand hyperexcitability and atypical connectivity in autism spectrum disorder
af: Ravishankar, M
Udgivet: (2015) -
Schizophrenia: neural architecture, brain regional differences, and changes with age
af: Bakhshi, K
Udgivet: (2013) -
NMDA Receptors Subunits, Medical Conditions Involved in, and Their Roles as Drug Targets
af: Mohamed Omer
Udgivet: (2020-07-01)