D-amino acid oxidase, D-serine and the dopamine system: their interactions and implications for schizophrenia

<p>D-amino acid oxidase (DAO) is a flavin-dependent enzyme that is expressed in the mammalian brain. It is the metabolising enzyme of several D-amino acids, including D serine, which is an endogenous agonist at the glycine co-agonist site of the glutamatergic NMDA receptor. As such, regulation...

وصف كامل

التفاصيل البيبلوغرافية
المؤلف الرئيسي: Betts, J
مؤلفون آخرون: Harrison, P
التنسيق: أطروحة
اللغة:English
منشور في: 2012
الموضوعات: