D-amino acid oxidase, D-serine and the dopamine system: their interactions and implications for schizophrenia

<p>D-amino acid oxidase (DAO) is a flavin-dependent enzyme that is expressed in the mammalian brain. It is the metabolising enzyme of several D-amino acids, including D serine, which is an endogenous agonist at the glycine co-agonist site of the glutamatergic NMDA receptor. As such, regulation...

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Bibliografiska uppgifter
Huvudupphovsman: Betts, J
Övriga upphovsmän: Harrison, P
Materialtyp: Lärdomsprov
Språk:English
Publicerad: 2012
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