Studies on immunoreceptor activation and SARS-CoV-2 RBD/ACE2 interactions

Studies on immunoreceptor activation and SARS-CoV-2 RBD/ACE2 interactions

<p>The immune system must maintain a very fine balance recognising threats without damaging healthy cells and it uses cell surface non-catalytic tyrosine phosphorylated receptors (NTRs) to achieve this. In order to study this complex behaviour this work has taken a reductionist approach, using...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awdur:	Barton, MI
Awduron Eraill:	van der Merwe, A
Fformat:	Traethawd Ymchwil
Iaith:	English
Cyhoeddwyd:	2022
Pynciau:	Immunology

Eitemau Tebyg

Bionics design of affinity peptide inhibitors for SARS-CoV-2 RBD to block SARS-CoV-2 RBD-ACE2 interactions
gan: Xiaofeng Liu, et al.
Cyhoeddwyd: (2023-01-01)

Molecular basis for antiviral activity of two pediatric neutralizing antibodies targeting SARS-CoV-2 Spike RBD
gan: Yaozong Chen, et al.
Cyhoeddwyd: (2023-01-01)

Vimentin is an important ACE2 co-receptor for SARS-CoV-2 in epithelial cells
gan: Jeffrey Arrindell, et al.
Cyhoeddwyd: (2022-11-01)

Protein-protein conjugation enhances the immunogenicity of SARS-CoV-2 receptor-binding domain (RBD) vaccines
gan: Puthupparampil V. Scaria, et al.
Cyhoeddwyd: (2022-08-01)

Neutralizing nanobodies bind SARS-CoV-2 spike RBD and block interaction with ACE2
gan: Huo, J, et al.
Cyhoeddwyd: (2020)

Exploring the Role of Glycans in the Interaction of SARS-CoV-2 RBD and Human Receptor ACE2
gan: Kien Nguyen, et al.
Cyhoeddwyd: (2021-05-01)

Thermodynamic analysis of the interactions between human ACE2 and spike RBD of Betacoronaviruses (SARS‐CoV‐1 and SARS‐CoV‐2)
gan: Agnieszka Rombel‐Bryzek, et al.
Cyhoeddwyd: (2023-01-01)

Exploring the disruption of SARS-CoV-2 RBD binding to hACE2
gan: Camryn Carter, et al.
Cyhoeddwyd: (2023-10-01)

Study of Potential Blocking Peptides Targeting the SARS-CoV-2 RBD/hACE2 Interaction
gan: Sara M. Villada-Troncoso, et al.
Cyhoeddwyd: (2024-09-01)

Design of a stabilized RBD enables potently neutralizing SARS-CoV-2 single-component nanoparticle vaccines
gan: Thayne H. Dickey, et al.
Cyhoeddwyd: (2023-03-01)

RBD Double Mutations of SARS-CoV-2 Strains Increase Transmissibility through Enhanced Interaction between RBD and ACE2 Receptor
gan: Siddharth Sinha, et al.
Cyhoeddwyd: (2021-12-01)

RBD trimer mRNA vaccine elicits broad and protective immune responses against SARS-CoV-2 variants
gan: Qingtai Liang, et al.
Cyhoeddwyd: (2022-04-01)

SARS-CoV-2 variants impact RBD conformational dynamics and ACE2 accessibility
gan: Mariana Valério, et al.
Cyhoeddwyd: (2022-10-01)

Effects of common mutations in the SARS-CoV-2 Spike RBD and its ligand, the human ACE2 receptor on binding affinity and kinetics
gan: Barton, MI, et al.
Cyhoeddwyd: (2021)

An Immunoreceptor-Targeting Strategy with Minimalistic C3b Peptide Fusion Enhances SARS-CoV-2 RBD mRNA Vaccine Immunogenicity
gan: Chiu CT, et al.
Cyhoeddwyd: (2024-07-01)

Lethal synergy between SARS-CoV-2 and Streptococcus pneumoniae in hACE2 mice and protective efficacy of vaccination
gan: Tarani Kanta Barman, et al.
Cyhoeddwyd: (2022-06-01)

Protocol for infecting and monitoring susceptible k18-hACE2 mice with SARS-CoV-2
gan: Joana Couto, et al.
Cyhoeddwyd: (2023-06-01)

Analyzing the interaction of human ACE2 and RBD of spike protein of SARS-CoV-2 in perspective of Omicron variant
gan: Arijit Samanta, et al.
Cyhoeddwyd: (2022-03-01)

Structure-Based Virtual Screening and Identification of Potential Inhibitors of SARS-CoV-2 S-RBD and ACE2 Interaction
gan: Jiacheng Xiong, et al.
Cyhoeddwyd: (2021-09-01)

Identification of SARS-CoV-2 S RBD escape mutants using yeast screening and deep mutational scanning
gan: Cyrus M. Haas, et al.
Cyhoeddwyd: (2021-12-01)

Sensitization of Non-permissive Laboratory Mice to SARS-CoV-2 with a Replication-Deficient Adenovirus Expressing Human ACE2
gan: Lok-Yin Roy Wong, et al.
Cyhoeddwyd: (2020-12-01)

Potential of umami molecules against SARS-CoV-2 (Omicron) S-RBD/hACE2 interaction: an in-silico study
gan: Zhiyong Cui, et al.
Cyhoeddwyd: (2025-05-01)

Studying the Effect of Glycosylation towards SARS-CoV-2 Spike RBD and ACE2 Interaction by Native Mass Spectrometry
gan: LUO Yu-xiang;HUANG Jing;LI Hui-lin
Cyhoeddwyd: (2022-11-01)

Analysis of RBD-ACE2 interactions in livestock species as a factor in the spread of SARS-CoV-2 among animals
gan: Mykyta Peka, et al.
Cyhoeddwyd: (2023-09-01)

Preclinical evaluation of a COVID-19 vaccine candidate based on a recombinant RBD fusion heterodimer of SARS-CoV-2
gan: Antonio Barreiro, et al.
Cyhoeddwyd: (2023-03-01)

Anti-human ACE2 antibody neutralizes and inhibits virus production of SARS-CoV-2 variants of concern
gan: Abigael E. Chaouat, et al.
Cyhoeddwyd: (2022-09-01)

COVID-19 patient serum less potently inhibits ACE2-RBD binding for various SARS-CoV-2 RBD mutants
gan: Daniel Junker, et al.
Cyhoeddwyd: (2022-05-01)

Cross-reactivity of SARS-CoV-2– and influenza A–specific T cells in individuals exposed to SARS-CoV-2
gan: Worarat Chaisawangwong, et al.
Cyhoeddwyd: (2022-09-01)

Potent neutralizing anti-SARS-CoV-2 human antibodies cure infection with SARS-CoV-2 variants in hamster model
gan: Maya Imbrechts, et al.
Cyhoeddwyd: (2022-08-01)

Selective SARS-CoV2 BA.2 escape of antibody Fc/Fc-receptor interactions
gan: Yannic C. Bartsch, et al.
Cyhoeddwyd: (2023-05-01)

Biochemical Characterization of SARS-CoV-2 Spike RBD Mutations and Their Impact on ACE2 Receptor Binding
gan: Abdullah Hoter, et al.
Cyhoeddwyd: (2022-05-01)

Antigenic Cross-Reactivity Between SARS-CoV-2 S1-RBD and Its Receptor ACE2
gan: Yen-Chung Lai, et al.
Cyhoeddwyd: (2022-05-01)

Effects of common mutations in the SARS-CoV-2 Spike RBD and its ligand, the human ACE2 receptor on binding affinity and kinetics
gan: Michael I Barton, et al.
Cyhoeddwyd: (2021-08-01)

Intronic regulation of SARS-CoV-2 receptor (ACE2) expression mediated by immune signaling and oxidative stress pathways
gan: Daniel Richard, et al.
Cyhoeddwyd: (2022-07-01)

Cross-reactive immunity to SARS-CoV-2 and related coronaviruses
gan: Jay, C
Cyhoeddwyd: (2023)

Structural and functional insights into the major mutations of SARS-CoV-2 Spike RBD and its interaction with human ACE2 receptor
gan: Arun Bahadur Gurung, et al.
Cyhoeddwyd: (2022-02-01)

A novel mouse AAV6 hACE2 transduction model of wild-type SARS-CoV-2 infection studied using synDNA immunogens
gan: Ebony N. Gary, et al.
Cyhoeddwyd: (2021-07-01)

Nonhuman primate antigenic cartography of SARS-CoV-2
gan: Annika Rössler, et al.
Cyhoeddwyd: (2025-01-01)

Mutational pressure promotes release of public CD8+ T cell epitopes by proteasome from SARS-CoV-2 RBD of Omicron and its current lineages
gan: Anna A. Kudriaeva, et al.
Cyhoeddwyd: (2025-03-01)

Microfluidic Diffusion Sizing Applied to the Study of Natural Products and Extracts That Modulate the SARS-CoV-2 Spike RBD/ACE2 Interaction
gan: Jason Fauquet, et al.
Cyhoeddwyd: (2023-12-01)