Multi-population genomic analysis of malaria parasites indicates local selection and differentiation at the gdv1 locus regulating sexual development

Parasites infect hosts in widely varying environments, encountering diverse challenges for adaptation. To identify malaria parasite genes under locally divergent selection across a large endemic region with a wide spectrum of transmission intensity, genome sequences were obtained from 284 clinical P...

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Main Authors: Duffy, C, Amambua-Ngwa, A, Ahouidi, A, Diakite, M, Awandare, G, Ba, H, Tarr, S, Murray, L, Stewart, L, D'Alessandro, U, Otto, T, Kwiatkowski, D, Conway, D
格式: Journal article
语言:English
出版: Springer Nature 2018