A circuit logic for sexually shared and dimorphic aggressive behaviors in Drosophila
Aggression involves both sexually monomorphic and dimorphic actions. How the brain implements these two types of actions is poorly understood. We have identified three cell types that regulate aggression in Drosophila: one type is sexually shared, and the other two are sex specific. Shared common ag...
| Main Authors: | , , , , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
Cell Press
2020
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| _version_ | 1797099094260318208 |
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| author | Chiu, H Hoopfer, ED Coughlan, ML Pavlou, HJ Goodwin, SF Anderson, DJ |
| author_facet | Chiu, H Hoopfer, ED Coughlan, ML Pavlou, HJ Goodwin, SF Anderson, DJ |
| author_sort | Chiu, H |
| collection | OXFORD |
| description | Aggression involves both sexually monomorphic and dimorphic actions. How the brain implements these two types of actions is poorly understood. We have identified three cell types that regulate aggression in Drosophila: one type is sexually shared, and the other two are sex specific. Shared common aggression-promoting (CAP) neurons mediate aggressive approach in both sexes, whereas functionally downstream dimorphic but homologous cell types, called male-specific aggression-promoting (MAP) neurons in males and fpC1 in females, control dimorphic attack. These symmetric circuits underlie the divergence of male and female aggressive behaviors, from their monomorphic appetitive/motivational to their dimorphic consummatory phases. The strength of the monomorphic → dimorphic functional connection is increased by social isolation in both sexes, suggesting that it may be a locus for isolation-dependent enhancement of aggression. Together, these findings reveal a circuit logic for the neural control of behaviors that include both sexually monomorphic and dimorphic actions, which may generalize to other organisms. |
| first_indexed | 2024-03-07T05:18:44Z |
| format | Journal article |
| id | oxford-uuid:de2445a4-e74a-4b4d-a66a-f790318bb19e |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T05:18:44Z |
| publishDate | 2020 |
| publisher | Cell Press |
| record_format | dspace |
| spelling | oxford-uuid:de2445a4-e74a-4b4d-a66a-f790318bb19e2022-03-27T09:30:05ZA circuit logic for sexually shared and dimorphic aggressive behaviors in DrosophilaJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:de2445a4-e74a-4b4d-a66a-f790318bb19eEnglishSymplectic ElementsCell Press2020Chiu, HHoopfer, EDCoughlan, MLPavlou, HJGoodwin, SFAnderson, DJAggression involves both sexually monomorphic and dimorphic actions. How the brain implements these two types of actions is poorly understood. We have identified three cell types that regulate aggression in Drosophila: one type is sexually shared, and the other two are sex specific. Shared common aggression-promoting (CAP) neurons mediate aggressive approach in both sexes, whereas functionally downstream dimorphic but homologous cell types, called male-specific aggression-promoting (MAP) neurons in males and fpC1 in females, control dimorphic attack. These symmetric circuits underlie the divergence of male and female aggressive behaviors, from their monomorphic appetitive/motivational to their dimorphic consummatory phases. The strength of the monomorphic → dimorphic functional connection is increased by social isolation in both sexes, suggesting that it may be a locus for isolation-dependent enhancement of aggression. Together, these findings reveal a circuit logic for the neural control of behaviors that include both sexually monomorphic and dimorphic actions, which may generalize to other organisms. |
| spellingShingle | Chiu, H Hoopfer, ED Coughlan, ML Pavlou, HJ Goodwin, SF Anderson, DJ A circuit logic for sexually shared and dimorphic aggressive behaviors in Drosophila |
| title | A circuit logic for sexually shared and dimorphic aggressive behaviors in Drosophila |
| title_full | A circuit logic for sexually shared and dimorphic aggressive behaviors in Drosophila |
| title_fullStr | A circuit logic for sexually shared and dimorphic aggressive behaviors in Drosophila |
| title_full_unstemmed | A circuit logic for sexually shared and dimorphic aggressive behaviors in Drosophila |
| title_short | A circuit logic for sexually shared and dimorphic aggressive behaviors in Drosophila |
| title_sort | circuit logic for sexually shared and dimorphic aggressive behaviors in drosophila |
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