A multiple scale model for tumor growth
We present a physiologically structured lattice model for vascular tumor growth which accounts for blood flow and structural adaptation of the vasculature, transport of oxygen, interaction between cancerous and normal tissue, cell division, apoptosis, vascular endothelial growth factor release, and...
| Main Authors: | , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2005
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| _version_ | 1797099095687430144 |
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| author | Alarcon, T Byrne, H Maini, P |
| author_facet | Alarcon, T Byrne, H Maini, P |
| author_sort | Alarcon, T |
| collection | OXFORD |
| description | We present a physiologically structured lattice model for vascular tumor growth which accounts for blood flow and structural adaptation of the vasculature, transport of oxygen, interaction between cancerous and normal tissue, cell division, apoptosis, vascular endothelial growth factor release, and the coupling between these processes. Simulations of the model are used to investigate the effects of nutrient heterogeneity, growth and invasion of cancerous tissue, and emergent growth laws. |
| first_indexed | 2024-03-07T05:18:45Z |
| format | Journal article |
| id | oxford-uuid:de258936-e1f3-4b48-8c3c-945bb5275ebd |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T05:18:45Z |
| publishDate | 2005 |
| record_format | dspace |
| spelling | oxford-uuid:de258936-e1f3-4b48-8c3c-945bb5275ebd2022-03-27T09:30:12ZA multiple scale model for tumor growthJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:de258936-e1f3-4b48-8c3c-945bb5275ebdEnglishSymplectic Elements at Oxford2005Alarcon, TByrne, HMaini, PWe present a physiologically structured lattice model for vascular tumor growth which accounts for blood flow and structural adaptation of the vasculature, transport of oxygen, interaction between cancerous and normal tissue, cell division, apoptosis, vascular endothelial growth factor release, and the coupling between these processes. Simulations of the model are used to investigate the effects of nutrient heterogeneity, growth and invasion of cancerous tissue, and emergent growth laws. |
| spellingShingle | Alarcon, T Byrne, H Maini, P A multiple scale model for tumor growth |
| title | A multiple scale model for tumor growth |
| title_full | A multiple scale model for tumor growth |
| title_fullStr | A multiple scale model for tumor growth |
| title_full_unstemmed | A multiple scale model for tumor growth |
| title_short | A multiple scale model for tumor growth |
| title_sort | multiple scale model for tumor growth |
| work_keys_str_mv | AT alarcont amultiplescalemodelfortumorgrowth AT byrneh amultiplescalemodelfortumorgrowth AT mainip amultiplescalemodelfortumorgrowth AT alarcont multiplescalemodelfortumorgrowth AT byrneh multiplescalemodelfortumorgrowth AT mainip multiplescalemodelfortumorgrowth |