Genomic disruption of the histone methyltransferase SETD2 in chronic lymphocytic leukaemia

Histone methyltransferases (HMTs) are important epigenetic regulators of gene transcription and are disrupted at the genomic level in a spectrum of human tumours including haematological malignancies. Using high-resolution single nucleotide polymorphism (SNP) arrays, we identified recurrent deletion...

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Asıl Yazarlar:	Parker, H, Rose-Zerilli, M, Larrayoz, M, Clifford, R, Edelmann, J, Blakemore, S, Gibson, J, Wang, J, Ljungström, V, Wojdacz, T, Chaplin, T, Roghanian, A, Davis, Z, Parker, A, Tausch, E, Ntoufa, S, Ramos, S, Robbe, P, Alsolami, R, Steele, A, Packham, G, Rodríguez-Vicente, A, Brown, L, McNicholl, F, Forconi, F, Pettitt, A, Hillmen, P, Dyer, M, Cragg, M, Chelala, C, Oakes, C, Rosenquist, R, Stamatopoulos, K, Stilgenbauer, S, Knight, S, Schuh, A, Oscier, D, Strefford, J
Materyal Türü:	Journal article
Dil:	English
Baskı/Yayın Bilgisi:	Nature Publishing Group 2016

Genomic disruption of the histone methyltransferase SETD2 in chronic lymphocytic leukaemia

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