MHC class II invariant chain–adjuvanted viral vectored vaccines enhances T cell responses in humans
Strategies to enhance the induction of high magnitude T cell responses through vaccination are urgently needed. Major histocompatibility complex (MHC) class II–associated invariant chain (Ii) plays a critical role in antigen presentation, forming MHC class II peptide complexes for the generation of...
Autors principals: | Esposito, I, Cicconi, P, D'Alise, AM, Brown, A, Esposito, M, Swadling, L, Holst, PJ, Bassi, MR, Stornaiuolo, M, Mori, F, Vassilev, V, Li, W, Donnison, T, Gentile, C, Turner, B, von Delft, A, Del Sorbo, M, Barra, F, Contino, AM, Abbate, A, Novellino, E, Thomsen, AR, Christensen, JP, Lahm, A, Grazioli, F, Ammendola, V, Siani, L, Colloca, S, Klenerman, P, Nicosia, A, Dorrell, L, Folgori, A, Capone, S, Barnes, E |
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Altres autors: | PEACHI Consortium |
Format: | Journal article |
Idioma: | English |
Publicat: |
American Association for the Advancement of Science
2020
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