MHC class II invariant chain–adjuvanted viral vectored vaccines enhances T cell responses in humans

Strategies to enhance the induction of high magnitude T cell responses through vaccination are urgently needed. Major histocompatibility complex (MHC) class II–associated invariant chain (Ii) plays a critical role in antigen presentation, forming MHC class II peptide complexes for the generation of...

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Bibliografiske detaljer
Main Authors: Esposito, I, Cicconi, P, D'Alise, AM, Brown, A, Esposito, M, Swadling, L, Holst, PJ, Bassi, MR, Stornaiuolo, M, Mori, F, Vassilev, V, Li, W, Donnison, T, Gentile, C, Turner, B, von Delft, A, Del Sorbo, M, Barra, F, Contino, AM, Abbate, A, Novellino, E, Thomsen, AR, Christensen, JP, Lahm, A, Grazioli, F, Ammendola, V, Siani, L, Colloca, S, Klenerman, P, Nicosia, A, Dorrell, L, Folgori, A, Capone, S, Barnes, E
Andre forfattere: PEACHI Consortium
Format: Journal article
Sprog:English
Udgivet: American Association for the Advancement of Science 2020