MHC class II invariant chain–adjuvanted viral vectored vaccines enhances T cell responses in humans

Strategies to enhance the induction of high magnitude T cell responses through vaccination are urgently needed. Major histocompatibility complex (MHC) class II–associated invariant chain (Ii) plays a critical role in antigen presentation, forming MHC class II peptide complexes for the generation of...

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Главные авторы:	Esposito, I, Cicconi, P, D'Alise, AM, Brown, A, Esposito, M, Swadling, L, Holst, PJ, Bassi, MR, Stornaiuolo, M, Mori, F, Vassilev, V, Li, W, Donnison, T, Gentile, C, Turner, B, von Delft, A, Del Sorbo, M, Barra, F, Contino, AM, Abbate, A, Novellino, E, Thomsen, AR, Christensen, JP, Lahm, A, Grazioli, F, Ammendola, V, Siani, L, Colloca, S, Klenerman, P, Nicosia, A, Dorrell, L, Folgori, A, Capone, S, Barnes, E
Другие авторы:	PEACHI Consortium
Формат:	Journal article
Язык:	English
Опубликовано:	American Association for the Advancement of Science 2020

MHC class II invariant chain–adjuvanted viral vectored vaccines enhances T cell responses in humans

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