MK-801 can facilitate passive avoidance memory when retention is not present in control animals, and can fail to facilitate when it is present.

The results confirm that NMDA receptor blockade can result in improved retention performance of mice in step-down passive avoidance. A series of behavioural variations and analyses revealed that memory in the task depended mainly on the appearance of the grid that had been associated with shock, rat...

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Bibliographic Details
Main Authors: Weiskrantz, L, Mondadori, C
Format: Journal article
Language:English
Published: 1991