Pairwise growth competitions identify relative fitness relationships among artemisinin resistant Plasmodium falciparum field isolates

BACKGROUND:Competitive outcomes between co-infecting malaria parasite lines can reveal fitness disparities in blood stage growth. Blood stage fitness costs often accompany the evolution of drug resistance, with the expectation that relatively fitter parasites will be more likely to spread in populat...

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Main Authors: Tirrell, AR, Vendrely, KM, Checkley, LA, Davis, SZ, McDew-White, M, Cheeseman, IH, Vaughan, AM, Nosten, FH, Anderson, TJC, Ferdig, MT
格式: Journal article
语言:English
出版: BioMed Central 2019