Polymorphisms in the MTHFR gene influence embryo viability and the incidence of aneuploidy
MTHFR is an important enzyme in the metabolism of folic acid and is crucial for reproductive function. Variation in the sequence of MTHFR has been implicated in subfertility, but definitive data are lacking. In the present study, a detailed analysis of two common MTHFR polymorphisms (c.677C>T and...
Main Authors: | Enciso, M, Sarasa, J, Xanthopoulou, L, Bristow, S, Bowles, M, Fragouli, E, Delhanty, J, Wells, D |
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Format: | Journal article |
Language: | English |
Published: |
Springer
2016
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