Ca2+ transport in pancreatic beta-cells during glucose stimulation of insulin secretion.

The role of Ca2+ in the regulation of insulin secretion was evaluated using beta-cell-rich pancreatic islets isolated from ob/ob-mice. The glucose stimulation of the secretory activity is supposed to result from accumulation of Ca2+ in the submembrane cytoplasmic space. It is likely that this proces...

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Autors principals: Hellman, B, Gylfe, E, Berggren, P, Andersson, T, Abrahamsson, H, Rorsman, P, Betsholtz, C
Format: Journal article
Idioma:English
Publicat: Informa Healthcare 1980