Recognition of a mononucleosomal histone modification pattern by BPTF via multivalent interactions.
Little is known about how combinations of histone marks are interpreted at the level of nucleosomes. The second PHD finger of human BPTF is known to specifically recognize histone H3 when methylated on lysine 4 (H3K4me2/3). Here, we examine how additional heterotypic modifications influence BPTF bin...
Main Authors: | Ruthenburg, A, Li, H, Milne, T, Dewell, S, McGinty, R, Yuen, M, Ueberheide, B, Dou, Y, Muir, T, Patel, D, Allis, C |
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Format: | Journal article |
Language: | English |
Published: |
2011
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