Hexokinase 2 as a novel selective metabolic target for rheumatoid arthritis
<strong>Objectives:</strong> Recent studies indicate that glucose metabolism is altered in rheumatoid arthritis (RA) fibroblast-like synoviocytes (FLS). Hexokinases (HKs) catalyse the first step in glucose metabolism, and HK2 constitutes the principal HK inducible isoform. We hypothesise...
Main Authors: | Bustamante, M, Oliveira, P, Garcia-Carbonell, R, Croft, A, Smith, J, Serrano, R, Sanchez-Lopez, E, Liu, X, Kisseleva, T, Hay, N, Buckley, C, Firestein, G, Murphy, A, Miyamoto, S, Guma, M |
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Format: | Journal article |
Published: |
BMJ Publishing Group
2018
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