Toll-like receptor-4 signaling drives persistent fibroblast activation and prevents fibrosis resolution in scleroderma
Significance: This review provides current overview of the emerging role of innate immunity in driving fibrosis, and preventing its resolution, in scleroderma (systemic sclerosis, SSc). Understanding the mechanisms of dysregulated innate immunity in fibrosis and SSc will provide opportunities for th...
Prif Awduron: | Bhattacharyya, S, Midwood, K, Yin, H, Varga, J |
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Fformat: | Journal article |
Iaith: | English |
Cyhoeddwyd: |
Mary Ann Liebert, Inc.
2017
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Eitemau Tebyg
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gan: Midwood, K, et al.
Cyhoeddwyd: (2009) -
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gan: Monaco, C, et al.
Cyhoeddwyd: (2011) -
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gan: Swati Bhattacharyya, et al.
Cyhoeddwyd: (2018-10-01) -
Intrinsic danger: activation of Toll-like receptors in rheumatoid arthritis.
gan: Goh, F, et al.
Cyhoeddwyd: (2012) -
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gan: Tomonori Aoyama, et al.
Cyhoeddwyd: (2010-01-01)