Fluorescence resonance energy transfer-based analysis of cAMP dynamics in live neonatal rat cardiac myocytes reveals distinct functions of compartmentalized phosphodiesterases.

Fluorescence resonance energy transfer-based analysis of cAMP dynamics in live neonatal rat cardiac myocytes reveals distinct functions of compartmentalized phosphodiesterases.

Cardiac myocytes have provided a key paradigm for the concept of the compartmentalized cAMP generation sensed by AKAP-anchored PKA. Phosphodiesterases (PDEs) provide the sole route for degrading cAMP in cells and are thus poised to regulate intracellular cAMP gradients. PDE3 and PDE4 represent the m...

Ամբողջական նկարագրություն

Մատենագիտական մանրամասներ
Հիմնական հեղինակներ:	Mongillo, M, McSorley, T, Evellin, S, Sood, A, Lissandron, V, Terrin, A, Huston, E, Hannawacker, A, Lohse, M, Pozzan, T, Houslay, MD, Zaccolo, M
Ձևաչափ:	Journal article
Լեզու:	English
Հրապարակվել է:	2004

Նմանատիպ նյութեր

Measuring dynamic changes in cAMP using fluorescence resonance energy transfer.
‌: Evellin, S, և այլն
Հրապարակվել է: (2004)

Phosphodiesterases and compartmentalized cAMP signalling in the heart.
‌: Zaccolo, M
Հրապարակվել է: (2006)

Compartmentalized phosphodiesterase-2 activity blunts beta-adrenergic cardiac inotropy via an NO/cGMP-dependent pathway.
‌: Mongillo, M, և այլն
Հրապարակվել է: (2006)

Phosphodiesterases and subcellular compartmentalized cAMP signaling in the cardiovascular system.
‌: Stangherlin, A, և այլն
Հրապարակվել է: (2012)

Compartmentalized cAMP/PKA signalling regulates cardiac excitation-contraction coupling.
‌: Lissandron, V, և այլն
Հրապարակվել է: (2006)

PGE(1) stimulation of HEK293 cells generates multiple contiguous domains with different [cAMP]: role of compartmentalized phosphodiesterases.
‌: Terrin, A, և այլն
Հրապարակվել է: (2006)

Discrete microdomains with high concentration of cAMP in stimulated rat neonatal cardiac myocytes.
‌: Zaccolo, M, և այլն
Հրապարակվել է: (2002)

Restricted diffusion of a freely diffusible second messenger: Mechanisms underlying compartmentalized cAMP signalling
‌: Zaccolo, M, և այլն
Հրապարակվել է: (2006)

Restricted diffusion of a freely diffusible second messenger: mechanisms underlying compartmentalized cAMP signalling.
‌: Zaccolo, M, և այլն
Հրապարակվել է: (2006)

Imaging the cAMP-dependent signal transduction pathway
‌: Zaccolo, M, և այլն
Հրապարակվել է: (2005)

Imaging the cAMP-dependent signal transduction pathway.
‌: Zaccolo, M, և այլն
Հրապարակվել է: (2005)

Study of cyclic adenosine monophosphate microdomains in cells.
‌: Mongillo, M, և այլն
Հրապարակվել է: (2005)

Activation of PKA in cell requires higher concentration of cAMP than in vitro: implications for compartmentalization of cAMP signalling
‌: Koschinski, A, և այլն
Հրապարակվել է: (2017)

A phosphodiesterase 3B-based signaling complex integrates exchange protein activated by cAMP 1 and phosphatidylinositol 3-kinase signals in human arterial endothelial cells.
‌: Wilson, L, և այլն
Հրապարակվել է: (2011)

Analysis of compartmentalized cAMP: A method to compare signals from differently targeted FRET reporters
‌: Stangherlin, A, և այլն
Հրապարակվել է: (2014)

Analysis of compartmentalized cAMP: a method to compare signals from differently targeted FRET reporters.
‌: Stangherlin, A, և այլն
Հրապարակվել է: (2014)

The role of type 4 phosphodiesterases in generating microdomains of cAMP: large scale stochastic simulations.
‌: Oliveira, R, և այլն
Հրապարակվել է: (2010)

β-adrenergic- and muscarinic receptor-induced changes in cAMP activity in adult cardiac myocytes detected with FRET-based biosensor
‌: Warrier, S, և այլն
Հրապարակվել է: (2005)

Beta-adrenergic- and muscarinic receptor-induced changes in cAMP activity in adult cardiac myocytes detected with FRET-based biosensor.
‌: Warrier, S, և այլն
Հրապարակվել է: (2005)

Disruption of the cyclic AMP phosphodiesterase-4 (PDE4)-HSP20 complex attenuates the β-agonist induced hypertrophic response in cardiac myocytes.
‌: Sin, Y, և այլն
Հրապարակվել է: (2011)

Compartmentalisation of cAMP and Ca(2+) signals.
‌: Zaccolo, M, և այլն
Հրապարակվել է: (2002)

Improvement of a FRET-based indicator for cAMP by linker design and stabilization of donor-acceptor interaction.
‌: Lissandron, V, և այլն
Հրապարակվել է: (2005)

cAMP and cGMP signaling cross-talk: role of phosphodiesterases and implications for cardiac pathophysiology.
‌: Zaccolo, M, և այլն
Հրապարակվել է: (2007)

Local modulation of cystic fibrosis conductance regulator: cytoskeleton and compartmentalized cAMP signalling.
‌: Monterisi, S, և այլն
Հրապարակվել է: (2013)

Phosphodiesterases maintain signaling fidelity via compartmentalization of cyclic nucleotides.
‌: Lomas, O, և այլն
Հրապարակվել է: (2014)

Sustained exposure to catecholamines affects cAMP/PKA compartmentalised signalling in adult rat ventricular myocytes
‌: Fields, L, և այլն
Հրապարակվել է: (2015)

Role of membrane microdomains in compartmentation of cAMP signaling.
‌: Shailesh R Agarwal, և այլն
Հրապարակվել է: (2014-01-01)

A toolkit for real-time detection of cAMP: insights into compartmentalized signaling.
‌: Berrera, M, և այլն
Հրապարակվել է: (2008)

Compartmentalized cAMP Signaling Associated With Lipid Raft and Non-raft Membrane Domains in Adult Ventricular Myocytes
‌: Shailesh R. Agarwal, և այլն
Հրապարակվել է: (2018-04-01)

cGMP-cAMP interplay in cardiac myocytes: a local affair with far-reaching consequences for heart function.
‌: Stangherlin, A, և այլն
Հրապարակվել է: (2012)

The role of type 4 phosphodiesterases in generating microdomains of cAMP: large scale stochastic simulations.
‌: Rodrigo F Oliveira, և այլն
Հրապարակվել է: (2010-07-01)

cGMP signals modulate cAMP levels in a compartment-specific manner to regulate catecholamine-dependent signaling in cardiac myocytes.
‌: Stangherlin, A, և այլն
Հրապարակվել է: (2011)

Modulation of compartmentalized cyclic nucleotide signalling via local inhibition of phosphodiesterase activity
‌: Brescia, M, և այլն
Հրապարակվել է: (2016)

A complex phosphodiesterase system controls β-adrenoceptor signalling in cardiomyocytes
‌: Mongillo, M, և այլն
Հրապարակվել է: (2006)

A complex phosphodiesterase system controls beta-adrenoceptor signalling in cardiomyocytes.
‌: Mongillo, M, և այլն
Հրապարակվել է: (2006)

Molecular cloning and transient expression in COS7 cells of a novel human PDE4B cAMP-specific phosphodiesterase, HSPDE4B3.
‌: Huston, E, և այլն
Հրապարակվել է: (1997)

Phosphodiesterase 4 cAMP phosphodiesterases as targets for novel anti-inflammatory therapeutics
‌: Simon J MacKenzie
Հրապարակվել է: (2004-01-01)

Multiple Facets of cAMP Signalling and Physiological Impact: cAMP Compartmentalization in the Lung
‌: Martina Schmidt, և այլն
Հրապարակվել է: (2012-11-01)

Cardiomyocyte membrane structure and cAMP compartmentation produce anatomical variation in β2AR-cAMP responsiveness in murine hearts
‌: Wright, PT, և այլն
Հրապարակվել է: (2018)

Transgenic fruit-flies expressing a FRET-based sensor for in vivo imaging of cAMP dynamics.
‌: Lissandron, V, և այլն
Հրապարակվել է: (2007)