Identifying psychiatric diagnosis from missing mood data through the use of log-signature features

The availability of mobile technologies has enabled the efficient collection of prospective longitudinal, ecologically valid self-reported clinical questionnaires from people with psychiatric diagnoses. These data streams have potential for improving the efficiency and accuracy of psychiatric diagno...

Full description

Bibliographic Details
Main Authors: Wu, Y, Goodwin, GM, Lyons, T, Saunders, KEA
Format: Journal article
Language:English
Published: Public Library of Science 2022
_version_ 1797109315130097664
author Wu, Y
Goodwin, GM
Lyons, T
Saunders, KEA
author_facet Wu, Y
Goodwin, GM
Lyons, T
Saunders, KEA
author_sort Wu, Y
collection OXFORD
description The availability of mobile technologies has enabled the efficient collection of prospective longitudinal, ecologically valid self-reported clinical questionnaires from people with psychiatric diagnoses. These data streams have potential for improving the efficiency and accuracy of psychiatric diagnosis as well predicting future mood states enabling earlier intervention. However, missing responses are common in such datasets and there is little consensus as to how these should be dealt with in practice. In this study, the missing-response-incorporated log-signature method achieves roughly 74.8% correct diagnosis, with f1 scores for three diagnostic groups 66% (bipolar disorder), 83% (healthy control) and 75% (borderline personality disorder) respectively. This was superior to the naive model which excluded missing data and advanced models which implemented different imputation approaches, namely, k-nearest neighbours (KNN), probabilistic principal components analysis (PPCA) and random forest-based multiple imputation by chained equations (rfMICE). The log-signature method provided an effective approach to the analysis of prospectively collected mood data where missing data was common and should be considered as an approach in other similar datasets. Because of treating missing responses as a signal, its superiority also highlights that missing data conveys valuable clinical information.
first_indexed 2024-03-07T07:40:06Z
format Journal article
id oxford-uuid:deeb9b94-2bf8-4ad7-9cc1-55767bf49de1
institution University of Oxford
language English
last_indexed 2024-03-07T07:40:06Z
publishDate 2022
publisher Public Library of Science
record_format dspace
spelling oxford-uuid:deeb9b94-2bf8-4ad7-9cc1-55767bf49de12023-04-12T14:05:26ZIdentifying psychiatric diagnosis from missing mood data through the use of log-signature featuresJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:deeb9b94-2bf8-4ad7-9cc1-55767bf49de1EnglishSymplectic ElementsPublic Library of Science2022Wu, YGoodwin, GMLyons, TSaunders, KEAThe availability of mobile technologies has enabled the efficient collection of prospective longitudinal, ecologically valid self-reported clinical questionnaires from people with psychiatric diagnoses. These data streams have potential for improving the efficiency and accuracy of psychiatric diagnosis as well predicting future mood states enabling earlier intervention. However, missing responses are common in such datasets and there is little consensus as to how these should be dealt with in practice. In this study, the missing-response-incorporated log-signature method achieves roughly 74.8% correct diagnosis, with f1 scores for three diagnostic groups 66% (bipolar disorder), 83% (healthy control) and 75% (borderline personality disorder) respectively. This was superior to the naive model which excluded missing data and advanced models which implemented different imputation approaches, namely, k-nearest neighbours (KNN), probabilistic principal components analysis (PPCA) and random forest-based multiple imputation by chained equations (rfMICE). The log-signature method provided an effective approach to the analysis of prospectively collected mood data where missing data was common and should be considered as an approach in other similar datasets. Because of treating missing responses as a signal, its superiority also highlights that missing data conveys valuable clinical information.
spellingShingle Wu, Y
Goodwin, GM
Lyons, T
Saunders, KEA
Identifying psychiatric diagnosis from missing mood data through the use of log-signature features
title Identifying psychiatric diagnosis from missing mood data through the use of log-signature features
title_full Identifying psychiatric diagnosis from missing mood data through the use of log-signature features
title_fullStr Identifying psychiatric diagnosis from missing mood data through the use of log-signature features
title_full_unstemmed Identifying psychiatric diagnosis from missing mood data through the use of log-signature features
title_short Identifying psychiatric diagnosis from missing mood data through the use of log-signature features
title_sort identifying psychiatric diagnosis from missing mood data through the use of log signature features
work_keys_str_mv AT wuy identifyingpsychiatricdiagnosisfrommissingmooddatathroughtheuseoflogsignaturefeatures
AT goodwingm identifyingpsychiatricdiagnosisfrommissingmooddatathroughtheuseoflogsignaturefeatures
AT lyonst identifyingpsychiatricdiagnosisfrommissingmooddatathroughtheuseoflogsignaturefeatures
AT saunderskea identifyingpsychiatricdiagnosisfrommissingmooddatathroughtheuseoflogsignaturefeatures