Vacuolar and plasma membrane stripping and autophagic elimination of Toxoplasma gondii in primed effector macrophages
Apicomplexan protozoan pathogens avoid destruction and establish a replicative niche within host cells by forming a nonfusogenic parasitophorous vacuole (PV). Here we present evidence for lysosome-mediated degradation of Toxoplasma gondii after invasion of macrophages activated in vivo. Pathogen eli...
Main Authors: | Ling, Y, Shaw, M, Ayala, C, Coppens, I, Taylor, G, Ferguson, D, Yap, G |
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格式: | Journal article |
语言: | English |
出版: |
2006
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