Vacuolar and plasma membrane stripping and autophagic elimination of Toxoplasma gondii in primed effector macrophages

Apicomplexan protozoan pathogens avoid destruction and establish a replicative niche within host cells by forming a nonfusogenic parasitophorous vacuole (PV). Here we present evidence for lysosome-mediated degradation of Toxoplasma gondii after invasion of macrophages activated in vivo. Pathogen eli...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron: Ling, Y, Shaw, M, Ayala, C, Coppens, I, Taylor, G, Ferguson, D, Yap, G
Fformat: Journal article
Iaith:English
Cyhoeddwyd: 2006