Integrating genealogical and dynamical modelling to infer escape and reversion rates in HIV epitopes.
The rates of escape and reversion in response to selection pressure arising from the host immune system, notably the cytotoxic T-lymphocyte (CTL) response, are key factors determining the evolution of HIV. Existing methods for estimating these parameters from cross-sectional population data using or...
Κύριοι συγγραφείς: | Palmer, D, Frater, J, Phillips, R, McLean, A, McVean, G |
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Μορφή: | Journal article |
Γλώσσα: | English |
Έκδοση: |
2013
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Παρόμοια τεκμήρια
Παρόμοια τεκμήρια
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Integrating genealogical and dynamical modelling to infer escape and reversion rates in HIV epitopes.
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Efficient coalescent simulation and genealogical analysis for large sample sizes
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Efficient Coalescent Simulation and Genealogical Analysis for Large Sample Sizes.
ανά: Jerome Kelleher, κ.ά.
Έκδοση: (2016-05-01)