Integrating genealogical and dynamical modelling to infer escape and reversion rates in HIV epitopes.

Integrating genealogical and dynamical modelling to infer escape and reversion rates in HIV epitopes.

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The rates of escape and reversion in response to selection pressure arising from the host immune system, notably the cytotoxic T-lymphocyte (CTL) response, are key factors determining the evolution of HIV. Existing methods for estimating these parameters from cross-sectional population data using or...

Bibliografske podrobnosti
Main Authors:	Palmer, D, Frater, J, Phillips, R, McLean, A, McVean, G
Format:	Journal article
Jezik:	English
Izdano:	2013

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