Impact of reducing complement inhibitor binding on the immunogenicity of native neisseria meningitidis outer membrane vesicles
Neisseria meningitidis recruits host human complement inhibitors to its surface to down-regulate complement activation and enhance survival in blood. We have investigated whether such complement inhibitor binding occurs after vaccination with native outer membrane vesicles (nOMVs), and limits immuno...
Main Authors: | Daniels-Treffandier, H, de Nie, K, Marsay, L, Dold, C, Sadarangani, M, Reyes-Sandoval, A, Langford, P, Wyllie, D, Hill, F, Pollard, A, Rollier, C |
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Format: | Journal article |
Language: | English |
Published: |
Public Library of Science
2016
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