Impact of reducing complement inhibitor binding on the immunogenicity of native neisseria meningitidis outer membrane vesicles

Impact of reducing complement inhibitor binding on the immunogenicity of native neisseria meningitidis outer membrane vesicles

Neisseria meningitidis recruits host human complement inhibitors to its surface to down-regulate complement activation and enhance survival in blood. We have investigated whether such complement inhibitor binding occurs after vaccination with native outer membrane vesicles (nOMVs), and limits immuno...

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Những tác giả chính:	Daniels-Treffandier, H, de Nie, K, Marsay, L, Dold, C, Sadarangani, M, Reyes-Sandoval, A, Langford, P, Wyllie, D, Hill, F, Pollard, A, Rollier, C
Định dạng:	Journal article
Ngôn ngữ:	English
Được phát hành:	Public Library of Science 2016

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