Impact of reducing complement inhibitor binding on the immunogenicity of native neisseria meningitidis outer membrane vesicles

Neisseria meningitidis recruits host human complement inhibitors to its surface to down-regulate complement activation and enhance survival in blood. We have investigated whether such complement inhibitor binding occurs after vaccination with native outer membrane vesicles (nOMVs), and limits immuno...

詳細記述

書誌詳細
主要な著者: Daniels-Treffandier, H, de Nie, K, Marsay, L, Dold, C, Sadarangani, M, Reyes-Sandoval, A, Langford, P, Wyllie, D, Hill, F, Pollard, A, Rollier, C
フォーマット: Journal article
言語:English
出版事項: Public Library of Science 2016