Impact of reducing complement inhibitor binding on the immunogenicity of native neisseria meningitidis outer membrane vesicles

Neisseria meningitidis recruits host human complement inhibitors to its surface to down-regulate complement activation and enhance survival in blood. We have investigated whether such complement inhibitor binding occurs after vaccination with native outer membrane vesicles (nOMVs), and limits immuno...

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Váldodahkkit: Daniels-Treffandier, H, de Nie, K, Marsay, L, Dold, C, Sadarangani, M, Reyes-Sandoval, A, Langford, P, Wyllie, D, Hill, F, Pollard, A, Rollier, C
Materiálatiipa: Journal article
Giella:English
Almmustuhtton: Public Library of Science 2016